While adult stem cells are multipotent, embryonic stem cells are mostly pluripotent except of cells in the earliest stages of embryonic development (fertilized egg) that are totipotent. Stem cell niches where stem cells reside in an embryo or any given organ are defined as stem cell microenvironments. The fate of stem cells depends on the effect of the microenvironment. Stem cells – depending on the stimuli – have two main ways to replicate: either symmetrically resulting in two daughter cells with stem cell characteristics or asymmetrically yielding a daughter cell with stem and another daughter cell with differentiating cell characteristics (Figure II-2).
Photo provided by Pexels
I am sorry to hear about your daughter’s condition. Stem cell therapy is currently being evaluated for possible use in optic nerve damage. The research is slowly moving towards the clinic but will probably not be ready for clinical trials for a few more years. Dr. Dong Chen at Schepens’ Eye Institute is currently working in this area. To read more about his work, please see the following web link: Currently, there are three promising technologies for restoration of lost visual function: visual prosthetics, optogenetics and stem cell photoreceptor replacement therapy. To read more about visual prosthetics, see the following link:
To read more about optogenetics, see the following link:
To read more about stem cell therapy, see the following link:
Figure II-3: Types of stem cell replications II
Photo provided by Flickr
I am from India. I am suffering from RP. My gene defect is prph2. 2 of my brother and sister have the same genetic problem. Is it possible for us to take part in the stem cell trial
Free stem cell papers, essays, and research papers.
Our problem (my wife Carole) is her optic nerve went ischemic after a stroke which lodged an embolus in the artery feeding her optic nerve. Since she had only one good eye, she became totally blind six years ago.
Stem cell research to regenerate the optic nerve would be overwhelming for us!!
Information for Authors: Cell Stem Cell
This point causes much debate and anger of those opposed to stem cell research but they ultimately look at the process and not the form or result of it.
External factors influencing mesenchymal stem cell fate …
The fact that the cells may come from embryos is not an objection, because the embryos are going to die anyway." -- Stephen Hawking The phrase “stem cell” calls to mind images of controversy: Pro-life picketers outside abortion and in-vitro fertilization clinics, patients with chronic disabilities waiting on a cure, scientists in a lab experimenting with a petri dish....
Constitutively Active SMAD2/3 Are Broad-Scope …
Dear Manish, I am sorry to hear about your mother’s condition. It is unclear on how long it will take for stem cell treatments in the U.S. to become available in India. The trials must first demonstrate safety and efficacy in the U.S. before the FDA will consider approval. You may want to have your mother evaluated at one of the medical institutes in India that have expertise in treating retinal disease. Below is a list of centers in India: